منابع مشابه
Langerhans Granules in Fetal Keratinocytes
Langerhans granules, as reconstructed in three dimensions and interpreted by Sagebiel and Reed (13) and Wolff (17), are discs that in profile look like rods bounded by limiting membranes 50-60 A wide and terminated in vesicular formations. Internally, the rod-shaped portions of the disc demonstrate paracrystalline nets or lattices with a periodicity of 90 A . The presence of these granules has ...
متن کاملLangerhans Cells in Skin Lesions of Leprosy
Background: Langerhans cells are important in the pathogenesis of leprosy. A recent study reported that these cells were almost absent in the epidermis overlying lepromatous lesions. Objective: To investigate a possible relationship between the number of Langerhans cells and the histopathologic spectrum of lesions in patients with leprosy. Methods: An immunohistochemical staining for S100 prot...
متن کاملAntimicrobial peptide LL-37 produced by HSV-2-infected keratinocytes enhances HIV infection of Langerhans cells.
Herpes simplex virus (HSV)-2 shedding is associated with increased risk for sexually acquiring HIV. Because Langerhans cells (LCs), the mucosal epithelium resident dendritic cells, are suspected to be one of the initial target cell types infected by HIV following sexual exposure, we examined whether and how HSV-2 affects HIV infection of LCs. Although relatively few HSV-2/HIV-coinfected LCs wer...
متن کاملSpy-Game on Graphs
We define and study the following two-player game on a graph G. Let k ∈ N∗. A set of k guards is occupying some vertices of G while one spy is standing at some node. At each turn, first the spy may move along at most s edges, where s ∈ N∗ is his speed. Then, each guard may move along one edge. The spy and the guards may occupy same vertices. The spy has to escape the surveillance of the guards,...
متن کاملBuilding and breeding molecules to spy on cells and tumors.
Imaging of biochemical processes in living cells and organisms is essential for understanding how genes and gene products work together in space and time and in health and disease. Such imaging depends crucially on indicator molecules designed to maximize sensitivity and specificity. These molecules can be entirely synthetic, entirely genetically encoded macromolecules, or hybrid combinations, ...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2019
ISSN: 0022-202X
DOI: 10.1016/j.jid.2019.06.120